Source:
PEIR Digital Library – Pathology Education
Instructional Resource
Image #7:
Type: Micro
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. This area shows dilated acini forming “microglandular” structures.
Image #8:
Type: Micro
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. This tumor shows round cells with scant cytoplasm, slightly irregular nuclei, and distinct nucleoli.
Image #9:
Type: Micro
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. This tumor shows intense immunostaining for trypsin. Note the trypsin positivity of the normal acinar tissue (left) adjacent to the tumor (right).
Image #10: 414138
Type: Micro
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. Immunostaining for trypsin labels the apical portion of the tumor cells.
Image #11: 414139
Type: Micro
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. Immunostaining for CAM 5.2 (cytokeratins 8 and 18) labels all tumor cells.
Image #12:
Type: Micro
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. Immunostaining for synaptophysin labels some tumor cells.
Image #13: 414142
Type: EM
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. This electron micrograph shows tumor cells with many pleomorphic and rather small zymogen granules (mean diameter 400 to 500 nm; range 200 to 1000 nm), commonly oriented towards the luminal space. They are round and lack a halo between their homogenous dark-staining contents and the granule membrane (x6340).
Image #14: 414144
Type: Micro
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. This area of a cystic acinar cell carcinoma is composed of numerous microsysts of varying size.
Images and descriptions from the AFIP Atlas of Tumor Pathology.

IMAGES 1-7

BACK TO "PATHOLOGY IMAGES" PAGE

BACK TO MAIN PAGE