Source:
PEIR Digital Library – Pathology Education
Instructional Resource
Image #1:
Type: Gross
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. Cut surface of an acinar cell carcinoma displays large yellowish brown to red nodules, separated by fibrous strands and frequently showing necrotic foci.
Image #2:
Type: Micro
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. At low magnification the markedly cellular tumor tissue shows gross lobulation by broad fibrous strands. Within the large tumor lobules there is only scant stroma.
Image #3:
Type: Micro
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. This tumor shows a mixed pattern, with acinar areas alternating with trabecular and solid formations.
Image #4:
Type: Micro
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. The nuclei are somewhat irregular in size. In acinar formations they show a polarized arrangement.
Image #5: (414133)
Type: Micro
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. This tumor shows a pure acinar pattern, reminiscent of normal pancreatic acinar tissue.
Image #6: (414134)
Type: Micro
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. The tumor cells have abundant cytoplasm, which is finely granular and PAS positive in its’ apical portion.
Image #7:
Type: Micro
Organ/System: Pancreas
Description: Acinar Cell Carcinoma. This area shows dilated acini forming “microglandular” structures.
Images and descriptions from the AFIP Atlas of Tumor Pathology.

IMAGES 8-14

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